KRT17 antibody (AA 1-432)

Catalog No. ABIN5776077

This Mouse Monoclonal antibody specifically detects KRT17 in WB, IF, ELISA, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for KRT17 antibody (AA 1-432) (ABIN5776077)

Target: KRT17 (Keratin 17 (KRT17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT17 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: AT9F3

Product Details anti-KRT17 Antibody

Binding Specificity: AA 1-432

Purpose: Human Cytokeratin 17/KRT17 antibody

Purification: Purified

Immunogen: Recombinant human KRT17(1-432aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for KRT17

Target: KRT17 (Keratin 17 (KRT17))

Alternative Name: Cytokeratin 17/KRT17

Background: Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin 17 is involved in wound healing and cell growth, two processes that require rapid cytoskeletal remodeling. Keratinocytes deficient in keratin 17 exhibit abnormal Akt/mTOR signaling and fail to produce an increase in translation, cell size, or growth, these cells also exhibit abnormal 14-3-3 sigma localization.

NCBI Accession: NP_000413